Conference Proceedings
Natural History of the Relative Ellipsoid Zone Reflectivity in Age-Related Macular Degeneration
S Thiele, Z Wu, B Isselmann, M Pfau, RH Guymer, CD Luu
Ophthalmology Retina | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2022
Abstract
Purpose: Relative ellipsoid zone reflectivity (rEZR) has been reported to be reduced in intermediate age-related macular degeneration (iAMD). However, longitudinal changes in rEZR remain unknown. This study investigated the natural history of rEZR in iAMD and its association with risk factors for disease progression, including the presence or extent of drusen volume, reticular pseudodrusen (RPD), and pigmentary abnormalities (PAs). Design: Longitudinal observational study. Participants: Subjects with bilateral large drusen. Methods: Spectral-domain (SD) OCT images of both eyes from each participant were obtained every 6 months for 3 years. Using an automated rEZR determination approach, the ..
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Grants
Awarded by Macular Disease Foundation Australia
Funding Acknowledgements
National Health & Medical Research Council of Australia (Project Grant no.: APP1027624 (RHG, CDL) and fellowship grant no.: GNT1103013 (RHG). 2) Bupa Health Foundation, Australia (RHG, CDL). 3) BONFOR GEROK Program, Faculty of Medicine, University of Bonn, Grant No. O-137.0026 (ST). 4) Maria-vonLinden Program, University of Bonn (ST). 5) Werner Jackstadt Nachwuchspreis of the German RetinaSociety to ST. 6) BM-AXIS Program of the University of Bonn and University of Melbourne to ST. 7) TheCentre for Eye Research Australia receives operational infrastructure support from the VictorianGovernment.